News:

  • 2024/04/16:

    Inspiring and long-lasting collaboration with Daniel Khananshvili and Moshe Giladi from the Tel Aviv University on Na+/Ca2+ exchangers resulted in a nice joint paper in Commun Biol. Thank you guys for your hard work and persistence!

  • 2024/04/15:

    The 15th EFTMS workshop will start soon - on Wed, Apr 17, 2024. Dont miss the lecture of prof. Michael L. Gross lecture available also online. Check here.

  • 2024/03/21:

    Further insight into the function of an AsLOV2-FMN based singlet oxygen production provieded through a great collaboration with Erik Sedlak. Now published in Protein Science

  • 2024/03/08:

    Fantastic news - our collaboration with the Haitin group (Yoni and Moshe) brought surprising insights into the function of enigmatic intracellular chloride channels. And the sweet reward - the story made it to Nat Commun!

  • 2024/03/06:

    We have two more PhD position available. One on structural mass spec of prion proteins and membrane transporters and the other on clinical mass scpetrometry and method development. Apply till Apr 20!

  • 2024/03/04:

    Big welcome to Petr Jerabek. He has joined our group as a programmer and will help us with the development of fancy tools for MS data analysis in collaboration with Bruker.

  • 2024/02/14:

    We have a new visitor in our lab - Francesca Del Cioppo from the Uni Roma.

  • 2024/01/26:

    🕷🕷🕷Our lab ZOO is growing again. Mike's successor has just arrived! Welcome ❤ Mike II.

  • 2024/01/20:

    In 2023 we spent a lot of time working on different projects with Angel L. Pey from Uni of Grenada. Now the results are coming out. First one on AGT1 mutants is published in FEBS Lett. Thanks INSTRUCT and CIISB for support.

  • 2024/01/18:

    We are looking for PhD students! Position funded for 4 years in the field of structural MS and cool FT-MS top-down analysis - details here.

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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