News:

  • 2022/11/18:

    And yet another one piece (last one in 2022) with Angel Pey and Milagros Medina. Our collaborative effort on NQO1 active site mutations is now in FEBS J. And again thanks EU FT-ICR MS (H2020) for support.

  • 2022/10/13:

    This year it looks like a solid harvest of work conducted with Angel L. Pey from Uni of Grenada. Another joint paper, this time on structural effects induced by cavity making mutation on a two domain protein - PGK1. Paper now available in Sci Rep. Thanks EU FT-ICR MS (H2020) for support.

  • 2022/10/10:

    Congratulations to Lukas on BIOCEV's PhD Student Publication Award - our JACS paper on FFAP attracts attention 😉. Great collaboration with the Beier group and CF Plus Chemicals. Thanks CSF and H2020 for financial support and HPST for sponsoring this award.

  • 2022/09/13:

    Insight into the role of site-specific phosphorylation of human antioxidant and disease-associated flavoprotein NQO1 provided through great collaboration with teams of Angel L. Pey and Milagros Medina. Paper now available in Arch Biochem Biophys. Thanks EU FT-ICR MS (H2020) for support.

  • 2022/09/09:

    Congratulations to Bára on succesfull (and very nice) master thesis defense!

  • 2022/08/30:

    Nice work with Moshe and Yoni, this time on tweety proteins is finally out. Freely available in Commun. Biol.! Emelia and guys, thanks for great collaboration and thanks EU FT-ICR MS (H2020) for support.

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

  • 2022/07/22:

    Synopsis of Ales' Hippostruct MSCA project is available here.

  • 2022/04/22:

    Are you interested in structural mass spectrometry, method development ad/or membrane proteins? We are looking for Bc, MSc, PhD students and post-doc! Inquiries should be addressed to Petr Novak.

Structural characterization of biologicals and membrane proteins - Free EPIC-XS Online Workshop, February 9, 14:45-17:50 CET, 2023

Logo EPIC-XSEU Flag

The European Proteomics Infrastructure Consortium providing Access (EPIC-XS) consists of a unified network of experienced access providers and research groups who share a common goal: to facilitate the development and sustainability of proteomics exploration to all life science researchers within the European Union.

EPIC-XS has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 823839.

Speakers

Topics

  • Structural mass spectrometry
  • Antibody structure
  • Transmembrane proteins
  • Computational approaches

Program

Will be updated but spekaers are confirmed and timing settled

14:45 - 14:55
Participants joining, setting up connection
14:55 - 15:00
Welcome by chairperson, Michael Volny

Session 1 - ANTIBODIES

15:00 - 15:30
Introduction to antibody structure studies by mass spectrometry, Frank Sobott
15:30 - 15:50
Tuning HDX-MS pipeline for antibodies, Petr Man
15:50 - 16:10
Intact and top-down characterization of antibodies by high-resolution native MS, Maurits den Boer
16:10 - 16:20
Q&A with the three speakers moderated by Michael Volny
16:20 - 16:30
Break

Session 2 - TRANSMEMBRANE PROTEINS

16:30 - 17:00
Structural mass spectrometry of membrane proteins, Julian Langer
17:00 - 17:20
Radical labelling techniques applied to membrane proteins, Petr Novak
17:20 - 17:40
Probing the functional dynamics of native membrane proteins by HDX-MS, Argyris Politis
17:40 - 17:50
Q&A with the three speakers moderated by Michael Volny

Registration

The workshop is free but the registration is required. It is available HERE. The session will be hosted on Zoom platform.

The past 2022 EPIC-XS Webinars were a great success; don’t miss the event and join the 10th EPIC-XS Webinar on hot topics (antibodies and membrane proteins) in structural proteomics!

Organizers

  • Petr Novak
  • Petr Man
  • Michael Volny
  • Daniel Kavan