News:

Horizon 2020
EPIC-XS
EU FT-ICR MS

Important:

  • 2019/11/12:

    We are looking for post-doc and PhD to join our team and work on various projects using structural mass spectrometry! Inquiries should be addressed to Petr Novak.

  • 2019/03/27:

    We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.

  • 2018/01/03:

    Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.

  • 2017/12/20:

    Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

News

2019/11/12:

TNA access under EU_FT-ICR_MS H2020 Project gave rise to this nice paper on NQO1 dynamics. Collaboration with Angel L. Pey from the University of Granada, Spain.

2019/11/08:

Our collaboration with RECAMO team resulted in paper HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins. which is now available in BBA General Subjects.
Enjoy free author's access until Dec 27 (using the hyperlink above)!

2019/10/28:

Petr Novak joined the Editorial Board of Biomolecules.

2019/10/10:

Joint paper with Volf's lab showing identification of blood sources of hematophagous arthropods is now in PLOS Neglected Tropical Diseases..

2019/10/04:

Our new publication combining ambient ion landing of proteases with structural biology is now in Catalyst.

2019/09/27:

The EPIC-XS proposal submission system is now online. Proposal can be submitted here.

2019/09/26:

Our paper describing characterization of transcription factor/DNA interaction by structural mass spectrometry has just been accepted!

2019/09/25:

Collaboration between IMIC, IOCB and CF Plus Chemicals resulted in a publication which is now available in Chemistry journal.

2019/08/05:

5th Short Course on FT-ICR-MS aimed at "Basics of FT-ICR: dynamic harmonization and computer simulation" will be held in early October in Moscow. Apply now, no participation fee, accommodation and meals covered!

2019/07/24:

Preprint version of our paper combining structural MS approaches for characterization of transcription factor / DNA interaction is now available in Biomolecules.

2019/07/19:

Chromatin Proteomics Workshop coorganized by EPIC-XS H2020 consortium will be on Sep 22-27, 2019 in Greece. Deadline (Jul 29) is approaching!.

2019/07/15:


Two new papers dealing with HDX-MS are out. In one we contributed to very important community wide guidelines paper in Nat. Methods - Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Antoher one is a joint Anal. Chem. paper with Kasper Rand's lab on HDX-compatible digestion of membrane proteins.

2019/07/10:


Joint paper with Valasek's lab describing how chemical cross-linking helps in structural characterization of 40S ribosomal subunit interacting with eIFs is now available in Nucleic Acid Research.

2019/07/10:

Short course on High Resolution Tandem Mass Spectrometry of Biomolecules will be organized by the EU_FT-ICR_MS H2020 consortium. Save the date and place: Aug 21-23, 2019, Warwick. Register here.

2019/06/24:


Few years ago, we helped Petrak's lab with the development of transmembrane proteome analysis. We are happy that Jirka's team is pushing it further and even happier we still keep in touch as this resulted in another nice J Proteomics paper.

2019/06/15:


Deadline for the first round of Transnational access proposal submission to EPIC-XS is apporaching (30th June 2019).

2019/06/12:


Congratulations to our Bc students (Zuzka, Verča, Týna, Kamila and Jana) on successful defense of their Bc theses.

2019/05/31:


Congratulations to Lucka Wallenfels (Hernychová) on successful defense of her PhD thesis and other happy life events. All the best in the future Lucka!.

2019/05/06:

Attempts to fully uderstand and somehow unify chemical cross-linking pushed further through interlaboratory comparion in which we participated. Read more in this community-wide Analytical Chemistry paper.

2019/05/05:

Short course on Ion-molecule reactions: fundamental and analytical aspects will be organized by the EU_FT-ICR_MS H2020 consortium. Save the date and place: June 25-27, 2019, Roma. Register here.

2019/04/29:

New publication about oligomerisation of NK cell receptors evaluated using homo-FRET and high resolution mass spectrometry - colaboration with Marek Cebecauer's group - is online in the International Journal of Molecular Sciences.

2019/03/02:

Advanced Users School on FT-ICR background will be organized by the EU_FT-ICR_MS H2020 consortium. Save the date and place: Apr 14-Apr18, 2019, Lisbon. Register here.

2019/01/26:

Joint paper with Ales Hnizda on structural characterization of pyrophosphatase NUDT15 and its thiopurine intolerance causing mutations is now available in Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics.

2018/11/28:

We recieved funding from Czech Science Foundation to study protein structure by reactive radical footprinting and top-down mass spectrometry.

2018/11/20:

Paper on Hsp70 dimerization - our collaboration with RECAMO team - has just been accepted in Mol Cell Proteomics.