News:

  • 2025/05/11:

    Well, it took some time, but we’ve finally brought HDX analysis of the Cl⁻/H⁺ antiporter to a high-resolution, high-throughput level, allowing analysis of numerous conditions and pH-matching time points — and the timing couldn’t have been better. Our findings align beautifully with cryo-EM structures from groups at Stanford and offer key insights into the mechanism of chloride/proton transport. The preprint is now live on BioRxiv. Great work, Jasmin and Luky!

  • 2025/05/11:

    That was the first time we started doing fast HDX at low temperature and were locked with Paja in a cold room - cis-PT times. Now the story goes out through a collaborative effort of three groups, led by the Haitin group! Nature *Whatever*, here we come!

  • 2025/04/30:

    Alan's work on coupling a q-TOF mass spectrometer to a synchrotron is now out in Phys. Chem. Chem. Phys.. Check out how protein ions can be dissociated using tools not typically accessible in mass spectrometry.

  • 2025/04/25:

    Get ready to take the next step in your career journey! Join us for the SPIDoc's Career Day, connect with professionals and discover diverse career pathways. When: May 16, 2025. Where: Biocev, CZ or online. See more details in the flyer.

  • 2025/04/16:

    A new paper, led by our current and former students (Valča, Rosi and Michael) shows how combining novel isotopically labeled, MS-cleavable cross-linkers with DIA-MS acquisition improves the description of structural changes in therapeutic proteins.

  • 2025/04/03:

    Great news! Our MSCA Doctoral Network proposal, ProtAIomics, has successfully passed the evaluation stage and is now invited for Grant Agreement Preparation. We look forward to contributing to this pan-European collaboration aimed at making mass spectrometry data interpretation less tedious.

  • 2025/04/01:

    Growing again. New PhD student Marta Cruz 🇵🇹; has already been there for a short stay. Now she returned for several years. Good luck with your PhD project and welcome Marta!

  • 2025/03/31:

    Some fantastic news! Friday, March 28, was a great day for our three PhDs – Marek🎉 👏, Michal🎉 👏, and Lukáš🎉 👏 – as they successfully defended their theses. Congratulations to our new doctors, and thank you for all your work and outstanding presentations!

  • 2025/03/31:

    Let’s talk about… well, 💩 . It might not sound pleasant, but our MALDI chip test significantly speeds up the detection of bacteria responsible for severe gut infections—preventing complications that could lead to systemic sepsis. Faster results lead to better treatment and improved patient outcomes.

  • 2025/03/24:

    Great news for barbecue lovers. Say goodbye to worries about botulism poisoning—thanks to our MS-based test that makes Botulinum detection faster and more affordable. This simple method is 100 times quicker, cheaper than the standard approach and, best of all, requires no animal testing!

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Important:

People

Laboratory is located in the BIOCEV center in Vestec. You can find us in labs J1.011-13, D2.004 and offices J1.006-008, D2.011.

Alumni

  • David ADÁMEK (MSc 2012) – Medical Manager at Roche and Podcaster!
  • Vítězslav BRINSA (PhD 2020-22) working with Aleš at the 1st Faculty of Medicine, Charles University
  • Martin ČONKA (MSc 2012) – Research Fellow at ExBio
  • Lada DLABOLOVÁ (MSc 2024)
  • Jan FIALA (PhD 2021) – Postdoctoral Fellow at Albert Heck's lab (Utrecht University, NL)
  • František FILANDR (PhD 2020) – Postdoctoral Fellow at the University of Calgary
  • Růžena FILANDROVÁ (LIŠKOVÁ) (PhD 2021) – Postdoctoral Fellow at the University of Calgary + 👶
  • Barbora FILIPOVÁ (Bc 2018) – chasing 🦘
  • Lukáš FOJTÍK (PhD 2024) – R&D at SOTIO
  • Pavel HANČ (MSc 2011) – Postdoctoral Fellow at Harvard Medical School
  • Jiří HAUSNER (MSc 2014)
  • Aleš HNÍZDA (junior scientist 2020-22) - Group leader at the 1st Faculty of Medicine, Charles University
  • Barbora JIREČKOVÁ (MSc 2022) - faculty hospital Vinohrady
  • Tereza KADAVÁ (MSc 2022) – pursuing PhD at at Albert Heck's lab (Utrecht University, NL)
  • Alan KÁDEK (PhD 2016) – Postdoctoral Fellow at Heinrich Pette Institute & European XFEL, Hamburg (🍔+🍺+⚓) till 8/2021. Now back home! (btw, should this be in the Alumni section? 😵)
  • Kristýna KOTÝNKOVÁ (MSc 2011) – Postdoctoral Researcher at Boston University School of Medicine
  • Veronika KÚDELOVÁ (Bc 2019)
  • Jan KUKLA (MSc 2014) – PRO.MED.CS
  • Zuzana MATOUŠKOVÁ (MSc 2020)
  • Alexander MELIKOV (MSc 2024)
  • Hynek MRÁZEK (post-doc 2012-2014) – IQVIA RDS
  • Kamila PELECHOVÁ (Bc 2019)
  • Marek POLÁK (PhD 2024) – playing with gators and huge magnets at the National High Magnetic Field Laboratory, Florida
  • Eliška POSPÍŠILOVÁ (MSc 2012)
  • Valérie PROCHÁZKOVÁ (Bc/MSc 2023) – 🍷 🐹 🍸
  • Michal ROSŮLEK (PhD) – researcher at Lonza
  • Daniel ROZBESKÝ (PhD 2013) – Junior group leaded at Charles University (BioCeV) after nice Post-doc at Oxford
  • Jana ŘEHÁKOVÁ (Bc 2019) - brewing 🍺
  • Kristián SKÁLA (MSc 2017)
  • Lukáš SLAVATA (PhD) – representative at HSPT s.r.o. / Agilent
  • Jitka SMETANOVÁ (MSc 2018)
  • Petra SVOBODOVÁ (DAREBNÁ) (MSc 2015)
  • Šárka SVOBODOVÁ (Bc 2018)
  • Kristýna ŠINTÁKOVÁ (Bc 2019)
  • Vyacheslav TRETYACHENKO (Bc 2013)
  • Karel VALIŠ (post-doc 2011-2021)
  • Maria A. VAN AGTHOVEN (senior scientist 2021-2023) – scientist at the Université de Rouen
  • Pavla VAŇKOVÁ (PhD 2020) – Staff scientist at IBT CAS / BioCeV - Center for Molecular Structure
  • František VOSTÁREK (MSc 2012)
  • Lucie WALLENFELS (HERNYCHOVÁ) (PhD 2019) – PharmInvent/PrimeVigilance
  • Ghazaleh YASSAGHI (post-doc 2017-2019) – Pfizer
  • Romana ZÁHUMENSKÁ (MSc 2017)
  • Eva ZÁKOUCKÁ (MSc 2014) – ⛷ ☕ 🥤 🧁 🍰
  • Valentyn II. THE BETTA FISH (lab fish). We keep memorries of your beauty.
  • Mike I. - THE ITSY BITSY SPIDER (lab spider) – currently catching 🪰 in 🕷 ☁️ and singing his favourite song