News:

  • 2021/02/05:

    Nice colaboration with Erik Sedlak's group on cytochrome c oxidation is now available in Int J Biol Macromol. Thanks EU_FT-ICR_MS H2020 Project for supporting this trans-national access! Enjoy 50 days of free access using the link above (till Mar 27, 2021).

  • 2021/01/31:

    New joint paper with Ales, from the times he was not part of our lab. FEBS J paper on Ku70/80 intramolecular interactions combining cryoEM and structural MS.

  • 2021/01/08:

    Collaboration with the Ludwig lab resulted in another paper on wood degrading enzymes. This time about chimeric CDHs in ACS Catalysis.

  • 2020/12/18:

    Paper on TEAD1-DNA interaction is now published in Structure. Enjoy 50 days of free access (till Feb 4, 2021).

  • 2020/12/14:

    Congratulations to Paja, now officially PhD in biochemistry!

  • 2020/12/11:

    Our HDX workflow combined with Ruza's experience on protein-DNA interaction studies was compiled into Methods Mol. Biol. chapter that has just been published.

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

  • 2021/02/03:

    EPIC-XS starts organization of regular workshops/webinars. The first one, on N-terminal processing and proteolysis will be on Feb 25, 2021.

  • 2021/02/03:

    Call for EPIC-XS proposals is open till March 31, 2021. Next round will be till Mar 31, 2021! Submit via the online submission system.

  • 2020/07/15:

    Visitors coming to our lab from abroad should consult the web page of the Czech Ministry of Health regarding COVID-19 related travel restrictions.

  • 2020/06/02:

    We are looking for post-doc and PhD to join our team and work on various projects using structural mass spectrometry! Inquiries should be addressed to Petr Novak.

  • 2019/03/27:

    We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.

  • 2018/01/03:

    Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.

  • 2017/12/20:

    Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

People

Laboratory is located in the BIOCEV center in Vestec. You can find us in labs J1.011-13, D2.004 and offices J1.006-008, D2.011.

Alumni

  • František FILANDR (PhD 2020) – Postdoctoral Fellow at the University of Calgary
  • Alan KÁDEK (PhD 2016) – Postdoctoral Fellow at Heinrich Pette Institute & European XFEL, Hamburg
  • Hynek MRÁZEK (post-doc 2012-2014) – Project manager at Pharmaceutical Research Associates
  • Daniel ROZBESKÝ (PhD 2013) – Postdoctoral Fellow at University of Oxford, Division of Structural Biology
  • Pavla VAŇKOVÁ (PhD 2020) – Staff scientist at IBT CAS / BioCeV - Center for Molecular Structure
  • Lucie WALLENFELS (HERNYCHOVÁ) (PhD 2019) – Scientific and Regulatory Specialist at PharmInvent/PrimeVigilance
  • Ghazaleh YASSAGHI (post-doc 2017-2019) – researcher in Dan Fabris lab, University at Albany
  • David ADÁMEK (MSc 2012) – Medical Science Liaison at Roche
  • Martin ČONKA (MSc 2012) – Research Fellow at ExBio
  • Barbora FILIPOVÁ (Bc 2018) - chasing 🦘
  • Pavel HANČ (MSc 2011) – Postdoctoral Fellow at Harvard Medical School
  • Jiří HAUSNER (MSc 2014) – Olympus
  • Kristýna KOTÝNKOVÁ (MSc 2011) – Postdoctoral Researcher at Boston University School of Medicine
  • Jan KUKLA (MSc 2014) – QC IS specialits at Ferring Léčiva a.s.
  • Veronika KÚDELOVÁ (Bc 2019)
  • Zuzana MATOUŠKOVÁ (MSc 2020)
  • Kamila PELECHOVÁ (Bc 2019)
  • Jana ŘEHÁKOVÁ (Bc 2019) - brewing 🍺
  • Kristián SKÁLA (MSc 2017) - PhD at J. Heyrovský Institute of Physical Chemistry of the CAS
  • Jitka SMETANOVÁ (MSc 2018) - chasing PhD at 2nd Medical Faculty, Charles University
  • Šárka SVOBODOVÁ (Bc 2018)
  • Kristýna ŠINTÁKOVÁ (Bc 2019) - working on her MSc in Biology, Faculty of Science, Charles University
  • František VOSTÁREK (MSc 2012) – Graduate student at Charles University
  • Eva ZÁKOUCKÁ (MSc 2014) – travelling around the world
  • Vyacheslav TRETYACHENKO (Bc 2013) - playing with never born proteins during his PhD at Charles University
  • Romana ZÁHUMENSKÁ (MSc 2017) - Graduate student at Jesseniova lekárska fakulta, Univerzita Komenského