Laboratory of Structural Biology and Cell Signaling

2019/11/12:
TNA access under EU_FT-ICR_MS H2020 Project gave rise to this nice paper on NQO1 dynamics. Collaboration with Angel L. Pey from the University of Granada, Spain.
2019/11/08:
Our collaboration with RECAMO team resulted in paper HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins. which is now available in BBA General Subjects.
Enjoy free author's access until Dec 27 (using the hyperlink above)!
2019/10/28:
Petr Novak joined the Editorial Board of Biomolecules.
2019/10/10:
Joint paper with Volf's lab showing identification of blood sources of hematophagous arthropods is now in PLOS Neglected Tropical Diseases..
2019/10/04:
Our new publication combining ambient ion landing of proteases with structural biology is now in Catalyst.
2019/09/27:
The EPIC-XS proposal submission system is now online. Proposal can be submitted here.

2019/11/12:
We are looking for post-doc and PhD to join our team and work on various projects using structural mass spectrometry! Inquiries should be addressed to Petr Novak.
2019/03/27:
We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.
2018/01/03:
Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.
2017/12/20:
Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

Výuka

Produkce a purifikace proteinu s využitím pro hmotnostní spektrometrii
školitel: Daniel Kavan
Počítačové zpracování dat z hmotnostní spektrometrie.
školitel: Daniel Kavan

Optimalizace chemického sítění proteinu s nukleovou kyselinou.
školitel: Petr Novák
Příprava afinitních nosičů pro klinickou diagnostiku.
školitel: Petr Pompach
Validace biologických terapeutik radikálovým značením proteinů.
školitel: Zdeněk Kukačka