Laboratory of Structural Biology and Cell Signaling

2019/10/10:
Joint paper with Volf's lab showing identification of blood sources of hematophagous arthropods is now in PLOS Neglected Tropical Diseases..
2019/10/04:
Our new publication combining ambient ion landing of proteases with structural biology is now in Catalyst.
2019/09/27:
The EPIC-XS proposal submission system is now online. Proposal can be submitted here.
2019/09/26:
Our paper describing characterization of transcription factor/DNA interaction by structural mass spectrometry has just been accepted!
2019/09/25:
Collaboration between IMIC, IOCB and CF Plus Chemicals resulted in a publication which is now available in Chemistry journal.
2019/08/05:
5th Short Course on FT-ICR-MS aimed at "Basics of FT-ICR: dynamic harmonization and computer simulation" will be held in early October in Moscow. Apply now, no participation fee, accommodation and meals covered!

2019/10/09:
We are looking for post-doc and PhD to join our team and work on structural mass spectrometry! Send inquiries to Petr Novak.
2019/03/27:
We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.
2018/01/03:
Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.
2017/12/20:
Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

Výuka

Produkce a purifikace proteinu s využitím pro hmotnostní spektrometrii
školitel: Daniel Kavan
Počítačové zpracování dat z hmotnostní spektrometrie.
školitel: Daniel Kavan

Optimalizace chemického sítění proteinu s nukleovou kyselinou.
školitel: Petr Novák
Příprava afinitních nosičů pro klinickou diagnostiku.
školitel: Petr Pompach
Validace biologických terapeutik radikálovým značením proteinů.
školitel: Zdeněk Kukačka