News:

  • 2025/10/07:

    Why so quiet in the lab? A big part of peterslab has relocated to Milano 🇮🇹 for the Structural Proteomics Symposium - with 4 talks and 7 posters on the program. Total peterslab invasion. 💥

  • 2025/10/03:

    New paper in N A R ! This project began back in 2020 through the H2020 project EPIC-XS, continued through an Instruct-Internship for Izabella, and kept evolving ever since… now finally reaching its sweet reward. A huge amount of work went into this – experiments capturing fast exchange in poorly structured proteins, and solid proof that DNA “tricks” in HDX-MS really do work. Very happy for Izabella, Dima, Paja, and of course Albane, who led the project.

  • 2025/09/26:

    No more suffering with scripts and macros - interpreting digestion data just got much easier. Our new software DigDig is now released, and the paper is out in Anal. Chem.. To celebrate this, we adopted a DikDik antelope at Prague Zoo - small, agile, and fast, just like our mascot should be. 🐐 Great work of Dan, Zuza and Jasmin!

  • 2025/09/22:

    A big day for Zuzka. Congratulations on nailing the PhD thesis defense 🎉 👏 and becoming a Dogtor🐶!

  • 2025/09/19:

    We just wrapped up an intense and rewarding week at the Structural MS Workshop at BIOCEV. It was a pleasure to work with such enthusiastic participants, and we thank everyone for their energy and contributions. Special thanks go to OP JAK Photomachines and SPIDoc’s MSCA Doctoral Network for funding, to Bruker for software support, and to CIISB Instruct-CZ for access to instrumentation.

  • 2025/08/11:

    Biophysics, HDX-MS and statistical modelling on track of antibiotic sequestration now out in ACS Bio Med Chem Au. Great collaboration with Athi N. Naganathan.

  • 2025/07/07:

    Great and fruitful collaboration with the Haitin group, this time on GGPPS (aka "another prenyl transferase"). Inspiring work on enzyme oligomerization using HDX and native MS. And a second PhD paper for Jasmin! 🎉

  • 2025/06/25:

    Congrats to Pepa 🎉 👏 on a successful PhD defense. Good luck in your furture steps Pepa and thanks for all the fun!

  • 2025/06/25:

    We are organizing a hands-on Structural MS workshop supported by the OP JAK – Photomachines project and the SPIDoc's doctoral network. This is a unique opportunity to learn sample preparation, analysis, and data processing in HDX-MS, native MS, top-down MS, and cross-linking MS - topped off with a touch of ultra-high-resolution mass spectrometry! Don’t miss your chance to register. The workshop will take place on September 15–19, 2025, at BIOCEV.

  • 2025/06/05:

    Great news! 🎉 👏 Ljubi has successfully defended her PhD thesis. Well done, Doctor!

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Important:

Structural Mass Spectrometry Workshop, Biocev, September 15–19, 2025

Logo OP-JAK Logo SPIDoc's

This workshop is organized through support from the OP JAK project Photomachines (CZ.02.01.01/00/22_008/0004624) and Marie Skłodowska Curie Action program HORIZON-MSCA-2022-DN project SPIDoc's (101120312EU).

Program

Monday, September 15
8:30 – 9:00Welcome and brief introduction
9:00 – 12:00Practicals I in groups
12:00 – 13:00Lunch
13:00 – 16:00Practicals II in groups
16:00 – ??:??BBQ mixer
Tuesday, September 16
9:00 – 12:00Practicals III in groups
12:00 – 13:00Lunch
13:00 – 14:30Lecture I — Native MS / Ion mobility
14:30 – 15:00Coffee break
15:00 – 16:30Lecture II — Chemical cross-linking MS
Wednesday, September 17
8:30 – 12:30Data processing I in groups
12:30 – 13:30Lunch
13:30 – 17:30Data processing II in groups
17:30 – 18:00Walk to the dinner venue
18:00 – 22:00Dinner
Thursday, September 18
9:00 – 10:30Lecture III — H/D exchange MS
10:30 – 11:00Coffee break
11:00 – 12:30Lecture IV — Ultra high-resolution MS
12:30 – 13:30Lunch
13:30 – 17:30Data processing III in groups
Friday, September 19
9:00 – 11:30Final discussion, Q&A, wrap-up
11:30 – 12:30Lunch

Protocols

Software and data

Location and transportation

  • Location: BIOCEV research center — Průmyslová 595, 252 50 Vestec
  • Public transport: “Vestec – BIOCEV” by buses 326 / 331 from Opatov (metro C). Alternatively, buses 332, 335, 337, 339 from Budějovická to “Vestec, Safina” followed by a 700–800 m walk.
  • Getting around Prague: use the metro. Trip planning: dpp.cz or the “PID Lítačka” app (also for buying tickets).
  • Tickets: a 90-minute transfer ticket is 40 CZK (metro / trams / buses). Validate paper tickets at first entry (yellow validator). Bus fare to BIOCEV from Prague is ~50 CZK (Prague + 1st outer zone).
  • Boarding note: since Aug 2025, you may board any door with a valid ticket (app). Otherwise, board front door, show the ticket, and tell the driver your stop: “Biocev” (or “Safina” from Budějovická).

Accommodation

  • Accommodation is not centrally organized; participants book their own. We recommend staying near bus routes to Vestec (ideally around Opatov — metro C) or anywhere on metro C south of “Pankrác”.
  • Options: in Vestec — U Krbu. In Prague near buses/metro C — Amedia Express Prague, Rezidence Emmy, Hotel Globus, Hotel Oya, Hotel Otar, or search for AirBnB around these areas.

Organizers

  • Petr Man
  • Alan Kádek
  • Petr Novák