News:

  • 2026/04/29:

    Maartje moved to another lab some time ago, but we still have things to finish. Published in JASMS, this work expands phase-corrected absorption mode processing for 2D mass spectrometry. This advancement doubles the signal-to-noise ratio and resolving power, significantly improving proteoform sequencing and small-molecule (ergot alkaloid) analysis.

  • 2026/04/27:

    The OP JAK InterMicro project has been instrumental in strengthening intra-institutional collaboration: functional and biophysical assays together with structural mass spectrometry revealed how calcium loading in the acylated segment acts as a molecular switch, controlling the structural folding and membrane penetration capacity of RTX toxins. Now out in J Biol Chem.

  • 2026/04/20:

    Fast, efficient, and online: This recent ACS Omega paper showcases a PNGaseRc-based deglycosylation column that streamlines analysis for therapeutic proteins and antibodies.

  • 2026/04/14:

    Is it time to move past formic acid? In this collaborative study in Anal. Chem., we contributed to establishing propionic acid as a robust alternative for LC-MS. This simple tweak boosts peptide IDs and offers a true “drop-in” way to increase proteome depth without compromising chromatography.

  • 2026/03/25:

    Wrapping up this final piece of research marks a bittersweet milestone. Initiated by our late colleague Angel Luis Pey and led to completion by Milagros Medina, this work reveals new insights into NQO1 function. To your memory, Angel, thank you for the inspiring collaboration.

  • 2026/01/09:

    Fantastic news! Huge dedication and hard work of Jasmin and Luky led to great data on CLC exchange coupling and this fitted perfectly to cryoEM and MD simulations obtained at Stanford by Maduke, Chiu and Dror labs! Joint paper is now out Nat Commun!

  • 2025/12/25:

    Perfect Xmas present 🎄 🎁 for Tomas - his first contribution to a paper and what's even better - it is in the Nat Commun! Collaboration with Roman Sobotka within the Photomachines project.

  • 2025/12/01:

    Great grant news - joint proposal by Ales Hnizda and Alan has been selected for support by the Czech Science Foundation (GACR)! What a continuation of their collaboration, where structural biology meets the clinic.

  • 2025/11/30:

    New Nat Commun paper with the Haitin&Giladi labs is out! Now, with the great molecular dynamics topping from the Giacomello group. Another step towards understanding the mechanism of cis-prenyltrasferases.

  • 2025/10/07:

    Why so quiet in the lab? A big part of peterslab has relocated to Milano 🇮🇹 for the Structural Proteomics Symposium - with 4 talks and 7 posters on the program. Total peterslab invasion. 💥

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