News:

  • 2023/11/03:

    Great news, Ljubi is back after maternity leave 👶 👶 !

  • 2023/10/26:

    Alan's contribution to the desing of sci-fi SPIDOC instrumentation - single particle imaging of protein complexes. Out in the Journal of Instrumentation. Cool!

  • 2023/10/26:

    Fruits of Maartje's work in our lab is starting to pop-out. Top-down 2D MS for proteoform characterization, now in Anal Chem.

  • 2023/10/02:

    If you want something really cool, let THE BOSS do the work! Great interlaboratory work on the online deglycosylation in HDX and proteomics now out in JASMS.

  • 2023/09/14:

    Great news! Our JACS paper on FFAP technology was awarded Hanus Prize 2023 Congratulations to Kuky, Luky and all others.

  • 2023/09/07:

    New MMB chapter on our HDX workflow full of tips and tricks, especially on immobilized protease columns. This time applied to antibodies and from Zuza.

  • 2023/08/25:

    Another masterpiece from the ongoing collaboration with the Veverka group!

  • 2023/07/18:

    Good bye Maartje, thank you for teaching us 2DMS and good luck in Rouen!

  • 2023/06/29:

    Zuza's lucky week - state doctoral exam done and second paper out!

  • 2023/06/01:

    Congratulations to Valča on a successful MSc defense and good luck in future PhD!

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

  • 2023/02/20:

    We are looking for java programmer. Position for two years. Collaboration with industrial partner - Bruker Daltonics! More details HERE.

  • 2022/07/22:

    Synopsis of Ales' Hippostruct MSCA project is available here.

  • 2022/04/22:

    Are you interested in structural mass spectrometry, method development ad/or membrane proteins? We are looking for Bc, MSc, PhD students and post-doc! Inquiries should be addressed to Petr Novak.

About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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