News:

  • 2021/06/15:

    We are organizing 2nd Advanced User School under the H2020 EU_FT-ICR_MS consortium. The school will be held in Prague/Vestec, Czech Republic on September 26-30, 2021 and will be stuffed with basics and applications of FT-ICR MS. Participation fee, accommodation and meals covered for 50 selected participants. Registration form can be found HERE. Deadline for application - Aug 23, 2021. Entry to CZ is regulated according to actual COVID situation.

  • 2021/05/31:

    Petr's collaboration with the Volf's lab and Austrian's parasitologists is now published in Parasit. Vectors.

  • 2021/04/21:

    Proteomic analysis of F. pinicola secretome leading to expression and characterization of two laccases (collaboration with the Ludwig Lab) has just been accepted in Enzyme Microb Technol

  • 2021/04/09:

    Structural analysis of human haptoglobin by FPOP and the benefits of ion mobility (TIMS/PASEF) for such analysis is now published in ACS Omega

  • 2021/03/25:

    Structural aspects of Von Willebrand factor binding and processing by metallopeptidase ADAMTS-13 studiedby integrative structural biology. Trans-national access via the EPIC-XS resulted in a joint publication in J. Mol. Biol.

  • 2021/03/10:

    The results of collaboration with the parasitology groups from Charles University and Morroco are now published in Transboundary and Emerging Diseases

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

  • 2021/07/20:

    Call for EPIC-XS proposals is open till Sep 30, 2021. However the pipeline is already quite full, so limited number of proposals can be accepted. Submit via the online submission system.

  • 2021/07/20:

    EPIC-XS organizes regular workshops/webinars. The fourht one, on Spatial proteomics, will be on Aug 26, 2021. Check EPIC-XS web site for details.

  • 2021/04/27:

    We are looking for post-doc with knowledge of excimer lasers and/or mass spec. Details here.

  • 2020/04/01:

    Are you interested in structural mass spectrometry, method development, transcription factors or membrane proteins? We are looking for Bc, MSc, PhD students and post-doc! Inquiries should be addressed to Petr Novak.

About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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