News:

  • 2020/02/14:

    Another TNA access under EU_FT-ICR_MS H2020 Project resulted in joint paper with Erik Sedlak from Kosice. Now published in Scientific Reports.

  • 2020/02/14:

    Cellulose degradation combo by Franta. Two papers arising from collaboration with Roland Ludwig and Daniel Kracher are out. One in Biomolecules and another in Biotechol. Biofuels.

  • 2020/01/23:

    Collaboration with Obsil's team on the interaction between 14-3-3 and caspase-2 was accepted in FEBS J.

  • 2020/01/21:

    We are proud of our IMIC colleagues Zdenek and Lucka for making this JACS paper a reality. And very happy to help with our MS skills!

  • 2020/01/08:

    Our new computational platform for biomolecular language processing called MatrixMotif is now available for download.

  • 2020/01/07:

    Petr Novak became the chair of the Czech Proteomics Society. Congratulations! :)

Horizon 2020
EPIC-XS
EU FT-ICR MS

Important:

  • 2020/01/07:

    Call for EPIC-XS proposals was closed on Dec 31, 2019. Get ready for next round which closes on March 31, 2020! Submit via the online submission system.

  • 2019/11/12:

    We are looking for post-doc and PhD to join our team and work on various projects using structural mass spectrometry! Inquiries should be addressed to Petr Novak.

  • 2019/03/27:

    We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.

  • 2018/01/03:

    Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.

  • 2017/12/20:

    Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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