News:

  • 2019/10/10:

    Joint paper with Volf's lab showing identification of blood sources of hematophagous arthropods is now in PLOS Neglected Tropical Diseases..

  • 2019/10/04:

    Our new publication combining ambient ion landing of proteases with structural biology is now in Catalyst.

  • 2019/09/27:

    The EPIC-XS proposal submission system is now online. Proposal can be submitted here.

  • 2019/09/26:

    Our paper describing characterization of transcription factor/DNA interaction by structural mass spectrometry has just been accepted!

  • 2019/09/25:

    Collaboration between IMIC, IOCB and CF Plus Chemicals resulted in a publication which is now available in Chemistry journal.

  • 2019/08/05:

    5th Short Course on FT-ICR-MS aimed at "Basics of FT-ICR: dynamic harmonization and computer simulation" will be held in early October in Moscow. Apply now, no participation fee, accommodation and meals covered!

Important:

  • 2019/10/09:

    We are looking for post-doc and PhD to join our team and work on structural mass spectrometry! Send inquiries to Petr Novak.

  • 2019/03/27:

    We are part of another Horizon 2020 project EPIC-XS (reg. no 823839) focused on the cutting edge proteomic techniques. This project provides Trans-National Access and also focuses on the development of the techniques.

  • 2018/01/03:

    Our lab is a part of Horizon 2020 project EU FT-ICR MS (reg. no 731077). Through this project you can access our expertise as well as other participating FT-ICR labs. Check Trans-National Acess web section for more details. Also, various FT-ICR focused courses and schools are organized by the labs participating in the project.

  • 2017/12/20:

    Bachelor and master theses are available in the lab. Areas of structrual biology, cutting edge mass spectrometry and cell signalling are awaiting new students. Check the tab Teaching.

About laboratory

Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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