News:

  • 2023/09/14:

    Great news! Our JACS paper on FFAP technology was awarded Hanus Prize 2023 Congratulations to Kuky, Luky and all others.

  • 2023/09/07:

    New MMB chapter on our HDX workflow full of tips and tricks, especially on immobilized protease columns. This time applied to antibodies and from Zuza.

  • 2023/08/25:

    Another masterpiece from the ongoing collaboration with the Veverka group!

  • 2023/07/18:

    Good bye Maartje, thank you for teaching us 2DMS and good luck in Rouen!

  • 2023/06/29:

    Zuza's lucky week - state doctoral exam done and second paper out!

  • 2023/06/01:

    Congratulations to Valča on a successful MSc defense and good luck in future PhD!

  • 2023/05/15:

    Congratulations to Terka on the best IMIC master thesis in 2022!

  • 2023/05/15:

    MALDI chips rocks! Pepa's first paper is out in Clinical Proteomics!

  • 2023/04/13:

    Thrilling collaboration with Klara Hlouchova on “non-existing proteins”. Our achievements got well accepted in Nat Ecol Evol. Thanks EPIC-XS for support.

  • 2023/04/12:

    And yet another one piece with Angel Pey and Milagros Medina. Our collaborative effort on NQO1 active site mutations is now fully published in FEBS J. And again thanks EU FT-ICR MS (H2020) for support.

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

  • 2023/02/20:

    We are looking for java programmer. Position for two years. Collaboration with industrial partner - Bruker Daltonics! More details HERE.

  • 2022/07/22:

    Synopsis of Ales' Hippostruct MSCA project is available here.

  • 2022/04/22:

    Are you interested in structural mass spectrometry, method development ad/or membrane proteins? We are looking for Bc, MSc, PhD students and post-doc! Inquiries should be addressed to Petr Novak.

About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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