Laboratory of Structural Biology and Cell Signaling

News:

2025/04/25:
Get ready to take the next step in your career journey! Join us for the SPIDoc's Career Day, connect with professionals and discover diverse career pathways. When: May 16, 2025. Where: Biocev, CZ or online. See more details in the flyer.
2025/04/16:
A new paper, led by our current and former students (Valča, Rosi and Michael) shows how combining novel isotopically labeled, MS-cleavable cross-linkers with DIA-MS acquisition improves the description of structural changes in therapeutic proteins.
2025/04/03:
Great news! Our MSCA Doctoral Network proposal, ProtAIomics, has successfully passed the evaluation stage and is now invited for Grant Agreement Preparation. We look forward to contributing to this pan-European collaboration aimed at making mass spectrometry data interpretation less tedious.
2025/04/01:
Growing again. New PhD student Marta Cruz 🇵🇹; has already been there for a short stay. Now she returned for several years. Good luck with your PhD project and welcome Marta!
2025/03/31:
Some fantastic news! Friday, March 28, was a great day for our three PhDs – Marek🎉 👏, Michal🎉 👏, and Lukáš🎉 👏 – as they successfully defended their theses. Congratulations to our new doctors, and thank you for all your work and outstanding presentations!
2025/03/31:
Let’s talk about… well, 💩 . It might not sound pleasant, but our MALDI chip test significantly speeds up the detection of bacteria responsible for severe gut infections—preventing complications that could lead to systemic sepsis. Faster results lead to better treatment and improved patient outcomes.
2025/03/24:
Great news for barbecue lovers. Say goodbye to worries about botulism poisoning—thanks to our MS-based test that makes Botulinum detection faster and more affordable. This simple method is 100 times quicker, cheaper than the standard approach and, best of all, requires no animal testing!
2025/02/24:
It’s official – Bruker has licensed our DeutEx software! This means faster HDX data processing is now available to users of timsTOFs, qTOFs, and FT-ICRs (MRMS). We're excited to bring DeutEx to more researchers through this collaboration.
2025/02/10:
Another step towards understanding protein folding and enzyme catalysis in crucial NQO1 redox flavoenzyme. Collaboration with Angel L. Pey (Granada) and Milagros Medina (Zaragoza) ready to go out. For now at least on BioRXiv.
2025/02/03:
Canadians 🇨🇦 are now making the second largest minority in the lab. Just for a while but we are happy to have May here. Welcome May Constabel from the MS-SPIDOC consortium. May will work with Alan and Ezgi on laser-armed 💥 big magnet 🧲.